Two of Three PCORnet Surveillance Grants Awarded to CAPriCORN Researchers

Two of the three recently awarded PCORnet Surveillance Grants went to researchers who are part of the Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN). The grants are intended to help connect researchers in PCORnet with public health practitioners and advocates to work on the collection and analysis of data needed for effective public health programming.

Yacob Tedla, PhD, Research Assistant Professor at CHIP, received a grant to identify a racially diverse cohort of newly diagnosed atrial fibrillation (AF) patients across 27 states to evaluate by race and zip code 1) the rate of direct oral anticoagulants (DOACs) and warfarin prescriptions within a year since AF diagnosis; and 2) incidence of stroke and bleeding after the diagnosis of AF. Investigators will examine geographic correlation between racial disparity in the prescription of oral anticoagulants and incidence of stroke and bleeding by states and regions of the Unites States. PCORnet Clinical Data Research Network partners include CAPriCORN, STAR, and ADVANCE.

Daniela Ladner, MD, MPH, Associate Professor of Surgery (Organ Transplantation) and Medical Social Sciences at the Feinberg School of Medicine, received a grant to monitor liver cirrhosis. Using an ensemble of validated diagnosis codes, procedure codes, and medication prescriptions initially tested on a CAPriCORN subset (HealthLNK), the multi-disciplinary team plans to monitor the true prevalence and incidence of this serious disease. The project has stakeholder support from the American Liver Foundation and the Illinois Department of Public Health. Through CAPriCORN’s collaboration with PCORnet partners STAR and REACHnet, the team aims to reach over 22.5 million patients throughout the US with this project — the largest of its kind in the field of cirrhosis.

CAPriCORN will support both investigators, working with the national network to provide input on building the data structure that awardees will be using for surveillance.

The Patient-Centered Clinical Research Network (PCORnet), developed by the Patient Centered Outcomes Research Institute (PCORI), helps people make educated healthcare decisions by supporting research relevant to their needs.

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